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David G Johnson Selected Research

E2F1 Transcription Factor

1/2020The E2F1 transcription factor and RB tumor suppressor moonlight as DNA repair factors.
11/2005Expression of transcription factor E2F1 and telomerase in glioblastomas: mechanistic linkage and prognostic significance.
8/2003Tumor formation in mice with conditional inactivation of Brca1 in epithelial tissues.
6/2002Inactivation of E2f1 enhances tumorigenesis in a Myc transgenic model.
3/2002ARF differentially modulates apoptosis induced by E2F1 and Myc.

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David G Johnson Research Topics

Disease

15Neoplasms (Cancer)
01/2020 - 03/2002
3Carcinogenesis
09/2011 - 01/2005
2Retinoblastoma (Glioblastoma, Retinal)
10/2019 - 01/2006
2Genomic Instability
08/2017 - 11/2016
2Squamous Cell Carcinoma of Head and Neck
10/2012 - 09/2011
1Breast Neoplasms (Breast Cancer)
11/2016
1Osteosarcoma (Osteogenic Sarcoma)
11/2016
1Oropharyngeal Neoplasms
09/2011
1Thymus Hyperplasia
06/2009
1Ataxia Telangiectasia (Louis Bar Syndrome)
01/2006
1Glioma (Gliomas)
11/2005
1Glioblastoma (Glioblastoma Multiforme)
11/2005
1Nijmegen Breakage Syndrome
04/2004

Drug/Important Bio-Agent (IBA)

5E2F1 Transcription FactorIBA
01/2020 - 03/2002
4Proteins (Proteins, Gene)FDA Link
08/2017 - 04/2004
3DNA (Deoxyribonucleic Acid)IBA
10/2019 - 01/2006
2Phosphotransferases (Kinase)IBA
11/2016 - 01/2006
2Oncogene Proteins (Oncogene Protein)IBA
08/2014 - 09/2011
2Codon (Codons)IBA
08/2014 - 09/2011
2Keratin-5 (Keratin 5)IBA
01/2006 - 06/2002
2Transcription Factors (Transcription Factor)IBA
01/2006 - 09/2004
1Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA
10/2019
1ChromatinIBA
08/2017
1MutagensIBA
06/2017
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
11/2016
11,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA
11/2016
1Poly(ADP-ribose) Polymerase InhibitorsIBA
11/2016
1CarcinogensIBA
08/2014
1Environmental CarcinogensIBA
08/2014
1Proline (L-Proline)FDA Link
08/2014
1E2F Transcription FactorsIBA
10/2012
1Retinoblastoma ProteinIBA
10/2010
1CyclinsIBA
06/2009
1Cyclin D1IBA
06/2009
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
11/2005
1LuciferasesIBA
11/2005
1Messenger RNA (mRNA)IBA
11/2005
1Telomerase (Telomerase Reverse Transcriptase)IBA
11/2005
1Biomarkers (Surrogate Marker)IBA
01/2005

Therapy/Procedure

3Therapeutics
06/2017 - 10/2010
1Chemoprevention
01/2005